PRODUCT IDENTIFICATION
H.S. CODE
TOXICITY
S(O)(=O)(=O)O.O1[C@H]([C@H]([C@@H]([C@H]([C@@H]1CO) O)O)NC)O [C@@H]1[C@]([C@@H](O[C@H]1O[C@H]1[C@H](O) [C@@ H](O)[C@@H]( [C@H]([C@@H]1NC(N)=N)O)NC(=N)N)C)( C=O)O.O1[C@H]([C@H ]([C@@H] ([C@H]([C@@H]1CO)O)O)NC) O[C@@H]1[C@]([C@@H](O[C@H ]1O[C@H]1 [C@@H]([C@H]([C@@H]([C@H]( [C@@H]1NC(N)=N)O)NC (=N)N)O)O) C)(C =O) O.S (=O) (=O)(O)O.S(=O)(=O)(O)O
CLASSIFICATION
Germicide, Bctericide, Disinfectant
EXTRA NOTES
EPA Pesticide Chemical Code 006310
Other RN: 298-39-5, 8018-05-1, 15105-93-8, 67479-32-7, 85027-84-5
PHYSICAL AND CHEMICAL PROPERTIES
AUTOIGNITION
NFPA RATINGS
REFRACTIVE INDEX
Stable under ordinary conditions
EXTERNAL LINKS & GENERAL DESCRIPTION
Wikipedia Linking - Streptomycin
Google Scholar Search - Streptomycin sulfate
Drug Information Portal (U.S. National Library of Medicine) - Streptomycin sulfate
PubChem Compound Summary - Streptomycin sulfate
Drug Bank - Streptomycin
KEGG (Kyoto Encyclopedia of Genes and Genomes) - Streptomycin
http://www.ebi.ac.uk/ - Streptomycin
http://www.ncbi.nlm.nih.gov/ - Streptomycin sulfate
http://www.nobelprize.org/
Streptomycin belongs to a group of compounds, known as antibiotics, which are produced by microorganisms and which possess the property of inhibiting the growth and even of destroying other microorganisms. Antibiotics vary greatly in their chemical nature, mode of action upon different organisms, and effect upon the animal body. The selective action of antibiotics upon bacteria and other microorganisms is known as the antibiotic spectrum. Some antibiotics are characterized by a very narrow spectrum, whereas others possess a wide range of activity. Some are active only against certain bacteria and not upon others, whereas some are active against fungi, and some against viruses. There is not only considerable qualitative variation in the activity of different antibiotics, but also wide quantitative differences. Antibiotics are produced by bacteria, fungi, actinomycetes, and to a limited extent by other groups of microorganisms.
Local:
Streptomycin is a water-soluble antibiotic drug that is principally used for the treatment of tuberculosis in conjunction with other drugs like isonicotinic acid hydrazide (isoniazid). Aminoglycoside is any of a group of antibiotics derived from various species of Streptomyces or Micromonosporaceae, while some of which are produced synthetically. Aminoglycosides inhibit bacterial protein synthesis by binding with the 30S ribosomal subunit and in some cases the 50S subunit, causing miscoding and thus inhibiting initiation and elongation during protein synthesis. They include;
- Amikacin
- Gentamicin
- Kanamycin
- Neomycin
- Netilmicin
- Paromomycin
- Streptomycin
- Tobramycin
Streptomycin is the first isolated aminoglycoside antibiotic derived from Streptomyces griseus. It is effective against a wide variety of aerobic gram-negative bacilli and some gram-positive bacteria, including mycobacteria. But Its use is limited because of the emergence of resistant strains.
APPEARANCE
IDENTIFICATION
pass (A,B,C,D,E)
SULFATE
3.0% max
pH
CLARITY OF SOLUTION
pass
LOSS ON DRYING
7.0% max
ASH
1.0% max
APPEARANCE
IDENTIFICATION
pass (A,B,C,D,E)
SULFATE
3.0% max
pH
CLARITY OF SOLUTION
pass
LOSS ON DRYING
7.0% max
ASH
1.0% max
pass
pass
FEED GRADE
APPEARANCE
IDENTIFICATION
CLARITY OF SOLUTION
90.0% min
MeOH
0.3% max
pH
3.0% max
LOSS ON DRYING
7.0% max
SULFATE
SULFATED ASH
1.0% max
HAZARD OVERVIEW
May impair fertility. May cause harm to the unborn child. Harmful if swallowed. May cause skin, eye, and respiratory tract irritation. May cause allergic respiratory and skin reaction.
GHS
Danger
PICTOGRAMS
HAZARD STATEMENTS
H302-H361
P STATEMENTS
P281
T:Toxic
RIS PHRASES
22-63
SAFETY PHRASES
36/37